3^rd International Conference on Hepatobiliary & Pancreatic Disorders September 17-18, 2018 | Philadelphia, Pennsylvania, USA

Masahiko Hirota has completed his PhD from Kumamoto Unversity. He is the director of Kumamoto Regional Medical Center, Japan, and the clinical professor of Department of Gastroenterological Surgery, Kumamoro University Medical School, Japan. He has published more than 250 papers in reputed journals.

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Jose R Torrealba has completed his MD in 1994 from the Central University of Venezuela. He then did a Post-doctoral fellowship in Molecular Biology at the University of Wisconsin, in Madison, Wisconsin and obtained his degree in Anatomic and Clinical Pathology from the Univeristy of Wisconsin. He specialized in Immunopathology of Transplantation at the University of Toronto, Canada in 2005. He held a job as Assistant Professor of Pathology at the University of Wisconsin until 2010 and currently is the Dr. George and Anne Race Distinguished Professor of Pathology at the Department of Pathology, UTSW Medical Center in Dallas, Texas.

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Jose Mario F. De Oliveira is a former post-doctorate fellow at the Brigham&Women´s hospital in Harvard Medical School and a deputy editor for diabetes in the global community forum of the British Medical Journal. He is a reviewer for a number of high impact peer review journlsals and has been an author or co-author for a number of peer review journals.

His research interest includes: Type 2 Diabetes, Obesity, Hypertension, Non-Communicable Diseases

Hem D. Shukla is Research Scientist in Department of Pharmaceutical Sciences at University of Maryland and adjunct Professor of Genomics in Notredame of Maryland University. He has also worked as Research Faculty in Department of Biology at Johns Hopkins University. Dr. Shukla has worked on proteomic analysis of oxidative stress response in BxPC-3 pancreatic cell lines and identification of biomarkers for pancreatic cancer. He has worked on “The Nrf2 mediated antioxidant defense against oxidative stress in pancreatic cancer cell lines and targets for therapeutic intervention”. He has shown elevated level of Nrf2 transcriptional factor in pancreatic cancer cell lines under oxidative stress which is phosphorylated by protein kinase C and affects phosphatidylinositol 3-kinase and MAP kinase pathways. After phosphorylation, Nrf2 translocates to the nucleus, binds AREs and transactivates detoxifying enzymes and antioxidant enzymes, such as glutathione S-transferase, and superoxide dismutase. The IPA analysis has suggested a potential role of Nrf2 under oxidative stress conditions.

Proteomic analysis of oxidative stress response in BxPC-3 pancreatic cell lines Identification of biomarkers for pancreatic cancer Nrf2 mediated antioxidant defense against oxidative stress in pancreatic cancer cell lines

He has completed his gradute course in 2009, finish my fellow program in HPB and Transplant surgery in 2014, and since then worked as HPB and transplant surgeon in two different and important schools in his state. Bayer Health & Care allowed speaker for Nexavar.

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